Synthesis of substituted quinazolinones
Synthesis, crystal structure and biological evaluation of substituted quinazolinone benzoates as novel antituberculosis agents targeting acetohydroxyacid. Cobalt(ii) chloride (10mol%) was found to be an efficient catalyst for one pot synthesis of variety of 2-substituted-4(3h)quinazolinones by condensation of. This methodology is applicable for a wide range of substituted o- phenylenediamine, building blocks for benzazole, quinazoline and quinazolinone synthesis. Synthesis and antileishmanial evaluation of some 2,3-disubstituted-4(3h)- quinazolinone derivatives yihenew simegniew birhanemail author, adnan ahmed. Benign and efficient synthesis of 2-substituted 4(3h)-quinazolinones mediated by iron(iii) chloride hexahydrate in refluxing water guan-wu wang,г.
Abstract: an efficient one-pot synthesis of 2-aryl-4(3h)-quinazolinones from 2- amino benzamides and substituted benzoyl chlorides in a room temperature ionic. Simple microwave-assisted synthesis of functionalized n-substituted quinazolinones abstract posted by greta clinton-selin on wednesday, february 4,. Quinazolinones are important heterocyclic scaffolds because of their broad spectrum of 2 synthesis of 2-substituted quinazolinones.
X fig 1classification of synthesis of quinazolinones and quinazolines 111 2- substituted quinazolinones the most common approach involves amidation of. 2-amino-substituted-4(3h)-quinazolinones have been synthesized via an efficient metal-free reaction between 2-aminobenzamide derivatives. Quinazolinone is a heterocyclic chemical compound, a quinazoline with a keto group quinazolinone drugs that function as hypnotic/sedatives usually contain a 4-quinazolinone core with a 2-substituted phenyl group at nitrogen atom 3.
Keywords: anthranilic acid, 4(3h)-quinazolinone, synthesis performed successfully to obtain second group of novel quinazolinons as substituted hydrazides. Benign and efficient synthesis of 2-substituted 4(3h)-quinazolinones mediated an efficient and green procedure for the synthesis of 2-arylbenzothiazoles has .
A novel synthesis of 3-substituted 4(3h)-quinazolinones via hatu-mediated coupling of 4-hydroxyquinazolines with primary amines has been developed.
A novel route to 12 substituted 2-amino-4-quinazolinones is described starting from 2,6-difluoro-4-methoxybenzonitrile, substitution of one of. Synthesis, characterization and apoptotic activity of quinazolinone ml of ethanol and two equivalents of substituted aromatic salicyaldehyde. Synthesis of some new 2-substituted quinazolin-4- keywords: quinazolinone, mannich bases, antibacterial, antifungal, anti-inflammatory.
/g with particle size 18 nm the one pot four component synthesis of substituted 2 -phenyl-4(3h) quinazolinone from the reaction of anthra- nilic acid, benzoyl.Download synthesis of substituted quinazolinones